⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14201590 | 0.75 | EPHX1 (0.34) | — | |
| SCHEMBL193396 | 0.75 | — | — | |
| SCHEMBL2066494 | 0.75 | — | — | |
| SCHEMBL6072132 | 0.74 | — | — | |
| SCHEMBL9288301 | 0.74 | — | — | |
| SCHEMBL1307154 | 0.74 | — | — | |
| SCHEMBL27460224 | 0.74 | — | — | |
| SCHEMBL624264 | 0.72 | — | — | |
| SCHEMBL3859693 | 0.72 | ADH1B (0.55) | — | |
| SCHEMBL17230654 | 0.72 | EPHX1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490367-B1 | IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS | GLAXO GROUP LTD (GB) | 2008-07-23 | — | — | EP | claimed |
| US-7348339-B2 | 2-(4-amino-furazan-3-yl)-1-ethyl-N-[(2R)-2-morpholinylmethyl]-1H-imidazo[4,5-c]pyridine-7-carboxamide; Mitogen- and Stress-Activated Protein (MSK) and Rho (guanosine triphosphate) 1 or 2 kinase inhibitor; neurodegenerative diaeases; antiinflammatory, anticarcinogenic, antiviral and antibacterial agent | GLAXO GROUP LIMITED (GB) | 2008-03-25 | — | — | US | claimed |
| US-20050197328-A1 | Imidazopyridine derivatives as kinase inhibitors | GLAXO GROUP LIMITED (GB) | 2005-09-08 | — | — | US | claimed |
| EP-1490367-A1 | IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-12-29 | — | — | EP | claimed |
| EP-1418909-A2 | 2-AMINO-4, 5-TRISUBSTITUTED THIAOLYL DERIVATIVES AND THEIR USE AGAINST AUTOIMMUNE DISEASES | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-05-19 | — | — | EP | claimed |
| WO-2003080610-A1 | IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-10-02 | — | — | WO | claimed |
| WO-2003015773-A2 | 2-AMINO-4,5-TRISUBSTITUTED THIAZOLYL DERIVATIVES AND THEIR USE AGAINST AUTOIMMUNE DISEASES | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-02-27 | — | — | WO | claimed |
| EP-1490367-B1 | IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS | GLAXO GROUP LTD (GB) | 2008-07-23 | — | — | EP | disclosed |
| US-7348339-B2 | 2-(4-amino-furazan-3-yl)-1-ethyl-N-[(2R)-2-morpholinylmethyl]-1H-imidazo[4,5-c]pyridine-7-carboxamide; Mitogen- and Stress-Activated Protein (MSK) and Rho (guanosine triphosphate) 1 or 2 kinase inhibitor; neurodegenerative diaeases; antiinflammatory, anticarcinogenic, antiviral and antibacterial agent | GLAXO GROUP LIMITED (GB) | 2008-03-25 | — | — | US | disclosed |
| US-20050197328-A1 | Imidazopyridine derivatives as kinase inhibitors | GLAXO GROUP LIMITED (GB) | 2005-09-08 | — | — | US | disclosed |
| EP-1490367-A1 | IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-12-29 | — | — | EP | disclosed |
| EP-1418909-A2 | 2-AMINO-4, 5-TRISUBSTITUTED THIAOLYL DERIVATIVES AND THEIR USE AGAINST AUTOIMMUNE DISEASES | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-05-19 | — | — | EP | disclosed |
| WO-2003080610-A1 | IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-10-02 | — | — | WO | disclosed |
| WO-2003015773-A2 | 2-AMINO-4,5-TRISUBSTITUTED THIAZOLYL DERIVATIVES AND THEIR USE AGAINST AUTOIMMUNE DISEASES | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-02-27 | — | — | WO | disclosed |