Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.30 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.30 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722027 | 0.92 | KHK (0.34) | F10MAPTHTTHTR6 | |
| SCHEMBL14101995 | 0.90 | F10 (0.38) | F10MAPTHTTHTR6 | |
| SCHEMBL4722250 | 0.87 | F10 (0.37) | F10MAOBHTR6 | |
| SCHEMBL4722255 | 0.87 | F10 (0.37) | F10MAOBHTR6 | |
| SCHEMBL4721425 | 0.86 | F10 (0.33) | F10MAPTHTTHTR6 | |
| SCHEMBL4719947 | 0.83 | BACE1 (0.33) | MAPTHTTHTR6CNR2 | |
| SCHEMBL4763492 | 0.83 | F10 (0.34) | F10MAPT | |
| SCHEMBL4721308 | 0.82 | ITGB2 (0.37) | F10 | |
| SCHEMBL4721312 | 0.82 | ITGB2 (0.37) | F10 | |
| SCHEMBL4722039 | 0.82 | ITGB2 (0.37) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |