SCHEMBL4722250 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	F10	P00742	6/20	0.37

▸	F2	P00734	1/20	0.37

▸	P2RX7	Q99572	1/20	0.34

▸	ROCK2	O75116	1/20	0.33

▸	RORC	P51449	1/20	0.33

▸	SOS1	Q07889	2/20	0.33

▸	MYC	P01106	2/20	0.32

▸	WDR5	P61964	2/20	0.32

▸	MAOB	P27338	1/20	0.32

▸	HTR6	P50406	1/20	0.32

▸	PDE3B	Q13370	2/20	0.32

▸	PDE3A	Q14432	2/20	0.32

▸	CTSS	P25774	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4722255	1.00	F10 (0.37)	F10F2P2RX7ROCK2RORC
SCHEMBL14101995	0.90	F10 (0.38)	F10F2HTR6
SCHEMBL4721312	0.89	ITGB2 (0.37)	F10
SCHEMBL4721308	0.89	ITGB2 (0.37)	F10
SCHEMBL4722039	0.89	ITGB2 (0.37)	F10
SCHEMBL4721425	0.89	F10 (0.33)	F10RORCHTR6CTSS
SCHEMBL4765735	0.88	F10 (0.36)	F10F2P2RX7ROCK2SOS1
SCHEMBL4765719	0.88	F10 (0.36)	F10F2P2RX7ROCK2SOS1
SCHEMBL4719604	0.87	F10 (0.33)	F10MAOBHTR6
SCHEMBL4723495	0.86	P2RX7 (0.36)	P2RX7RORCSOS1MYCWDR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1953147-A1	HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF	Japan Tobacco, Inc. (JP)	2008-08-06	—	—	EP	disclosed
EP-1953147-A1	HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF	Japan Tobacco, Inc. (JP)	2008-08-06	—	—	EP	disclosed