Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL941 | 0.77 | TSHR (0.40) | KDM4EGAATSHR | |
| SCHEMBL1056 | 0.77 | KDM4E (0.39) | KDM4EGAATSHR | |
| SCHEMBL7267947 | 0.76 | KDM4E (0.47) | KDM4EGAATSHR | |
| Hydrochloric Acid SCHEMBL7276912 | 0.75 | KDM4E (0.38) | KDM4EGAATSHR | |
| SCHEMBL8149691 | 0.68 | SMN1; SMN2 (0.31) | KDM4EGAA | |
| SCHEMBL8142567 | 0.66 | SMN1; SMN2 (0.47) | KDM4EGAATSHR | |
| SCHEMBL7274394 | 0.66 | KDM4E (0.36) | KDM4EGAATSHR | |
| SCHEMBL9321576 | 0.66 | KDM4E (0.40) | KDM4EGAATSHR | |
| Hydrochloric Acid SCHEMBL7277644 | 0.65 | KDM4E (0.36) | KDM4EGAATSHR | |
| SCHEMBL30720856 | 0.63 | HPGD (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360800-A | Tetrahydro-1H-pyrido[4,3-b]indol-1-one derivatives | GLAXO GROUP LIMITED (GB) | 1994-11-01 | — | — | US | disclosed |
| EP-0306323-A2 | Lactam derivatives | GLAXO GROUP LIMITED (GB) | 1989-03-08 | — | — | EP | disclosed |