Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7277644 | 0.98 | KDM4E (0.36) | KDM4EGAAHTTTSHR | |
| SCHEMBL632166 | 0.83 | KDM4E (0.34) | KDM4EGAAHTTTSHR | |
| SCHEMBL8176755 | 0.80 | TBXAS1 (0.36) | KDM4EGAA | |
| SCHEMBL6958742 | 0.80 | TBXAS1 (0.36) | KDM4EGAA | |
| SCHEMBL6964096 | 0.80 | TBXAS1 (0.36) | KDM4EGAA | |
| SCHEMBL6960237 | 0.80 | TBXAS1 (0.36) | KDM4EGAA | |
| SCHEMBL6956227 | 0.80 | TBXAS1 (0.36) | KDM4EGAA | |
| SCHEMBL14901212 | 0.75 | KDM4E (0.33) | KDM4EGAAHTTTSHR | |
| SCHEMBL6428241 | 0.73 | ALDH1A1 (0.38) | KDM4EGAASMN1; SMN2 | |
| SCHEMBL16125139 | 0.72 | KDM4E (0.31) | KDM4EGAAHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353983-B1 | Lactam derivatives | GLAXO GROUP LTD (GB) | 1996-05-29 | — | — | EP | disclosed |
| EP-0306323-B1 | Lactam derivatives | GLAXO GROUP LTD (GB) | 1994-09-21 | — | — | EP | disclosed |
| EP-0347229-A1 | Indole derivatives | GLAXO GROUP LIMITED (GB) | 1989-12-20 | — | — | EP | disclosed |
| EP-0306323-A2 | Lactam derivatives | GLAXO GROUP LIMITED (GB) | 1989-03-08 | — | — | EP | disclosed |