Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4762041 | 0.93 | ALDH1A1 (0.62) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL4718628 | 0.89 | ALDH1A1 (0.74) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL4761515 | 0.86 | ALDH1A1 (0.59) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL4717755 | 0.84 | KDM4E (0.58) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL4715024 | 0.84 | KDM4E (0.51) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL4761307 | 0.82 | KDM4E (0.54) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL4718932 | 0.82 | KDM4E (0.53) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL4718919 | 0.81 | ALDH1A1 (0.77) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL10807872 | 0.81 | KDM4E (0.52) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL10374014 | 0.81 | KDM4E (0.60) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230235-B1 | COMPOUNDS WITH ANTIBACTERIAL AND ANTIPARASITIC PROPERTIES | NEW PHARMA RES SWEDEN AB (SE) | 2008-06-11 | — | — | EP | claimed |