Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722012 | 0.91 | NPSR1 (0.71) | MAPTNPSR1LMNAGAAHTT | |
| SCHEMBL4724164 | 0.83 | NPSR1 (0.83) | MAPTNPSR1LMNAGAAHTT | |
| SCHEMBL4724101 | 0.83 | MAPT (0.65) | MAPTNPSR1LMNAGAAHTT | |
| SCHEMBL4724747 | 0.82 | NPSR1 (0.74) | MAPTNPSR1LMNAGAAHTT | |
| SCHEMBL4720311 | 0.81 | MAPT (0.63) | MAPTNPSR1LMNAGAAHTT | |
| SCHEMBL4722447 | 0.80 | MAPT (0.61) | MAPTNPSR1LMNAGAAHTT | |
| SCHEMBL4723874 | 0.78 | MAPT (0.59) | MAPTNPSR1LMNAGAAHTT | |
| SCHEMBL4722207 | 0.77 | MAPT (0.60) | MAPTNPSR1LMNAGAAHTT | |
| SCHEMBL4721647 | 0.76 | MAPT (0.76) | MAPTNPSR1LMNAGAAHTT | |
| SCHEMBL4723180 | 0.76 | NPSR1 (0.76) | MAPTNPSR1LMNAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |