Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.35 |
| ▸ | SLC16A1 | P53985 | 3/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721150 | 0.90 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DPTGS1 | |
| SCHEMBL4722274 | 0.89 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DPTGS1 | |
| SCHEMBL4720223 | 0.88 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DPTGS1 | |
| SCHEMBL4719764 | 0.88 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DPTGS1 | |
| SCHEMBL4723271 | 0.87 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DPTGS1 | |
| SCHEMBL4719190 | 0.87 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DPTGS1 | |
| SCHEMBL4722238 | 0.87 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DPTGS1 | |
| SCHEMBL14101992 | 0.86 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DPTGS1 | |
| SCHEMBL4722165 | 0.86 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4DPTGS1 | |
| SCHEMBL4719254 | 0.86 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |