Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 9/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4766563 | 0.93 | MAPT (0.52) | NPSR1MAPTMAPK1HTR6HTT | |
| SCHEMBL4718779 | 0.92 | MAPT (0.53) | NPSR1MAPTMAPK1HTR6HTT | |
| SCHEMBL4721382 | 0.92 | NPSR1 (0.44) | NPSR1MAPTMAPK1HTR6HTT | |
| SCHEMBL4723501 | 0.92 | MAPT (0.47) | NPSR1MAPTMAPK1HTR6HTT | |
| SCHEMBL4721830 | 0.92 | NPSR1 (0.44) | NPSR1MAPTMAPK1HTR6HTT | |
| SCHEMBL4719093 | 0.91 | NPSR1 (0.43) | NPSR1MAPTMAPK1HTR6HTT | |
| SCHEMBL4723959 | 0.91 | MAPT (0.44) | NPSR1MAPTMAPK1HTR6HTT | |
| SCHEMBL4721875 | 0.91 | NPSR1 (0.43) | NPSR1MAPTMAPK1HTR6HTT | |
| SCHEMBL4723990 | 0.90 | ALDH1A1 (0.49) | NPSR1MAPTMAPK1HTR6HTT | |
| SCHEMBL4722625 | 0.89 | NPSR1 (0.41) | NPSR1MAPTMAPK1HTR6HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |