Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | GAK | O14976 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721819 | 0.94 | MEN1 (0.42) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL4721837 | 0.90 | CYP1A2 (0.42) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL4724313 | 0.90 | CYP1A2 (0.42) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL4722204 | 0.90 | CYP1A2 (0.42) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL4723078 | 0.89 | CYP1A2 (0.41) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL4723982 | 0.89 | GAA (0.51) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL4724172 | 0.88 | CYP1A2 (0.41) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL4723765 | 0.88 | GAK (0.42) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL4764880 | 0.87 | PRKDC (0.43) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL4719606 | 0.87 | MEN1 (0.41) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |