Acetic Acid Butyl Ester

Acetic Acid Butyl Ester

SCHEMBL472065

CC(=O)O.CCCCOC(C)=O.OCCO

nearest known ligand 0.78

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Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid Butyl Ester. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.78
ATM Q13315 1/20 0.48
HCAR2 Q8TDS4 2/20 0.47
TSHR P16473 5/20 0.45
HPGD P15428 1/20 0.45
LMNA P02545 1/20 0.42
HSD17B10 Q99714 1/20 0.42
NAAA Q02083 1/20 0.42
ACHE P22303 7/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid Butyl Ester SCHEMBL11129197 0.96 ALDH1A1 (0.78) ALDH1A1ATMHCAR2TSHRHPGD
Acetic Acid Butyl Ester SCHEMBL117774 0.96 ALDH1A1 (0.86) ALDH1A1ATMHCAR2TSHRHPGD
Acetic Acid Butyl Ester SCHEMBL9131212 0.94 ALDH1A1 (0.75) ALDH1A1ATMHCAR2TSHRHPGD
Acetic Acid Butyl Ester SCHEMBL598803 0.93 ALDH1A1 (0.82) ALDH1A1ATMHCAR2TSHRHPGD
Acetic Acid Butyl Ester SCHEMBL29055253 0.93 ALDH1A1 (0.90) ALDH1A1ATMHCAR2TSHRHPGD
Acetic Acid Butyl Ester SCHEMBL29112143 0.93 ALDH1A1 (0.90) ALDH1A1ATMHCAR2TSHRHPGD
Acetic Acid Butyl Ester SCHEMBL28843487 0.93 ALDH1A1 (0.90) ALDH1A1ATMHCAR2TSHRHPGD
Acetic Acid Butyl Ester SCHEMBL232628 0.93 ALDH1A1 (0.90) ALDH1A1ATMHCAR2TSHRHPGD
Acetic Acid Butyl Ester SCHEMBL11216308 0.92 ALDH1A1 (0.72) ALDH1A1ATMHCAR2TSHRHPGD
Acetic Acid Butyl Ester SCHEMBL4872777 0.91 ALDH1A1 (0.78) ALDH1A1ATMHCAR2TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1874826-B1 COATING COMPOSITION COMPRISING A CELLULOSE MIXED ESTER EASTMAN CHEM CO (US) 2019-05-15 EP disclosed
EP-2301973-B1 Low molecular weight cellulose mixed esters and their use as low viscosity binders and modifiers in coating compositions EASTMAN CHEM CO (US) 2013-10-30 EP disclosed
EP-1603952-B1 LOW MOLECULAR WEIGHT CELLULOSE MIXED ESTERS AND THEIR USE AS LOW VISCOSITY BINDERS AND MODIFIERS IN COATING COMPOSITIONS EASTMAN CHEM CO (US) 2013-09-04 EP disclosed
US-8124676-B2 Basecoat coating compositions comprising low molecular weight cellulose mixed esters EASTMAN CHEMICAL COMPANY (US) 2012-02-28 US disclosed
EP-2411478-A1 REFINISH COATING COMPOSITIONS COMPRISING LOW MOLECULAR WEIGHT CELLULOSE MIXED ESTERS Eastman Chemical Company (US) 2012-02-01 EP disclosed
US-20110282049-A1 LOW MOLECULAR WEIGHT CELLULOSE MIXED ESTERS AND THEIR USE AS LOW VISCOSITY BINDERS AND MODIFIERS IN COATING COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 2011-11-17 US disclosed
US-8039531-B2 Low molecular weight cellulose mixed esters and their use as low viscosity binders and modifiers in coating compositions EASTMAN CHEMICAL COMPANY (US) 2011-10-18 US disclosed
US-8003715-B2 Low molecular weight cellulose mixed esters and their use as low viscosity binders and modifiers in coating compositions EASTMAN CHEMICAL COMPANY (US) 2011-08-23 US disclosed
EP-2328983-A1 BASECOAT COMPOSITIONS COMPRISING LOW MOLECULAR WEIGHT CELLULOSE MIXED ESTERS Eastman Chemical Company (US) 2011-06-08 EP disclosed
EP-2301973-A2 Low molecular weight cellulose mixed esters and their use as low viscosity binders and modifiers in coating compositions EASTMAN CHEMICAL COMPANY (US) 2011-03-30 EP disclosed
US-20070282038-A1 Methods for improving the anti-sag, leveling, and gloss of coating compositions comprising low molecular weight cellulose mixed esters EASTMAN CHEMICAL COMPANY 2007-12-06 US disclosed
EP-1603953-B1 LOW MOLECULAR WEIGHT CARBOXYALKYCELLULOSE ESTERS AND THEIR USE AS LOW VISCOSITY BINDERS AND MODIFIERS IN COATING COMPOSITIONS EASTMAN CHEM CO (US) 2007-11-14 EP disclosed
US-20070088105-A1 Low molecular weight cellulose mixed esters and their use as low viscosity binders and modifiers in coating compositions EASTMAN CHEMICAL COMPANY 2007-04-19 US disclosed
WO-2006116367-A1 LOW MOLECULAR WEIGHT CELLULOSE MIXED ESTERS AND THEIR USE AS LOW VISCOSITY BINDERS AND MODIFIERS IN COATING COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 2006-11-02 WO disclosed
EP-1603952-A1 LOW MOLECULAR WEIGHT CELLULOSE MIXED ESTERS AND THEIR USE AS LOW VISCOSITY BINDERS AND MODIFIERS IN COATING COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 2005-12-14 EP disclosed
EP-1603953-A1 LOW MOLECULAR WEIGHT CARBOXYALKYCELLULOSE ESTERS AND THEIR USE AS LOW VISCOSITY BINDERS AND MODIFIERS IN COATING COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 2005-12-14 EP disclosed
WO-2004083253-A1 LOW MOLECULAR WEIGHT CELLULOSE MIXED ESTERS AND THEIR USE AS LOW VISCOSITY BINDERS AND MODIFIERS IN COATING COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 2004-09-30 WO disclosed
WO-2004083254-A1 LOW MOLECULAR WEIGHT CARBOXYALKYCELLULOSE ESTERS AND THEIR USE AS LOW VISCOSITY BINDERS AND MODIFIERS IN COATING COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 2004-09-30 WO disclosed
US-20040181009-A1 Low molecular weight cellulose mixed esters and their use as low viscosity binders and modifiers in coating compositions EASTMAN CHEMICAL COMPANY 2004-09-16 US disclosed
US-20040180993-A1 Low molecular weight carboxyalkylcellulose esters and their use as low viscosity binders and modifiers in coating compositions EASTMAN CHEMICAL COMPANY 2004-09-16 US disclosed