Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | UGCG | Q16739 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 7/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | ALPI | P09923 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4719505 | 0.91 | PDE4A (0.35) | PDE4APDE4BPDE4CPDE4DUGCG | |
| SCHEMBL4721967 | 0.89 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DUGCG | |
| SCHEMBL4719850 | 0.86 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DUGCG | |
| SCHEMBL4722716 | 0.86 | NOTUM (0.38) | PDE4APDE4BPDE4CPDE4DUGCG | |
| SCHEMBL4722276 | 0.86 | UGCG (0.36) | PDE4APDE4BPDE4CPDE4DUGCG | |
| SCHEMBL4721533 | 0.86 | NOTUM (0.39) | PDE4APDE4BPDE4CPDE4DUGCG | |
| SCHEMBL4721217 | 0.86 | PDE4A (0.33) | PDE4APDE4BPDE4CPDE4DUGCG | |
| SCHEMBL4722323 | 0.86 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4DUGCG | |
| SCHEMBL4722220 | 0.85 | GRIA2 (0.35) | PDE4APDE4BPDE4CPDE4DUGCG | |
| SCHEMBL4724195 | 0.85 | F10 (0.42) | PDE4APDE4BPDE4CPDE4DUGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |