Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | F10 | P00742 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | UGCG | Q16739 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722947 | 0.94 | MAPT (0.39) | GRIA2UGCGACACBALDH1A1MAPT | |
| SCHEMBL4719850 | 0.89 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL4722276 | 0.89 | UGCG (0.36) | GRIA2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4721342 | 0.88 | PDE4A (0.34) | PDE4APDE4BPDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL4721967 | 0.87 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DF10 | |
| SCHEMBL4719026 | 0.86 | ACACB (0.38) | GRIA2SMN1; SMN2F10PTGS2UGCG | |
| SCHEMBL4719505 | 0.86 | PDE4A (0.35) | PDE4APDE4BPDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL4721533 | 0.85 | NOTUM (0.39) | PDE4APDE4BPDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL4720798 | 0.85 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL4721217 | 0.85 | PDE4A (0.33) | PDE4APDE4BPDE4CPDE4DSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |