Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722686 | 0.90 | NPSR1 (0.65) | MAPTNPSR1LMNAGAAAAK1 | |
| SCHEMBL4724738 | 0.86 | MAPT (0.60) | MAPTNPSR1LMNAGAAAAK1 | |
| SCHEMBL4720715 | 0.85 | MAPT (0.46) | MAPTNPSR1LMNAGAAAAK1 | |
| SCHEMBL4723562 | 0.85 | MAPT (0.45) | MAPTNPSR1LMNAGAAAAK1 | |
| SCHEMBL4721133 | 0.85 | MAPT (0.56) | MAPTNPSR1LMNAGAAHTT | |
| SCHEMBL4719649 | 0.85 | MEN1 (0.40) | MAPTNPSR1LMNAGAAHTT | |
| SCHEMBL4722439 | 0.85 | MEN1 (0.43) | MAPTNPSR1LMNAGAAHTT | |
| SCHEMBL4719701 | 0.85 | GAA (0.41) | MAPTNPSR1LMNAGAAHTT | |
| SCHEMBL4722264 | 0.84 | MAPT (0.47) | MAPTNPSR1LMNAGAAAAK1 | |
| SCHEMBL4719402 | 0.84 | MAPT (0.44) | MAPTNPSR1LMNAGAAAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |