Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.49 |
| ▸ | FLT3 | P36888 | 3/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721990 | 0.94 | GPR119 (0.48) | GPR119KDRFGFR1FLT1HTR2A | |
| SCHEMBL4720606 | 0.91 | GPR119 (0.52) | GPR119FLT3CDK2CDK6ACACB | |
| SCHEMBL4718867 | 0.90 | GPR119 (0.54) | GPR119FLT3CDK2CDK6ACACB | |
| SCHEMBL386924 | 0.89 | GPR119 (0.62) | GPR119CYP2C9 | |
| SCHEMBL4721995 | 0.89 | GPR119 (0.52) | GPR119FLT3CDK2CDK6KDR | |
| SCHEMBL4723434 | 0.88 | GPR119 (0.55) | GPR119FLT3CDK2CDK6ACACB | |
| SCHEMBL4720782 | 0.86 | GPR119 (0.58) | GPR119FLT3CDK2CDK6ACACB | |
| SCHEMBL4721009 | 0.85 | GPR119 (0.48) | GPR119FLT3CDK2CDK6KDR | |
| SCHEMBL4765631 | 0.84 | GPR119 (0.56) | GPR119FLT3CDK2CDK6ACACB | |
| SCHEMBL4719555 | 0.83 | GPR119 (0.52) | GPR119FLT3CDK2CDK6ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756084-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES AS MODULATORS OF METABOLISM AND THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARM INC (US) | 2008-11-26 | — | — | EP | claimed |