SCHEMBL4721785

SCHEMBL4721785

O=C1N=CC=C2N=CC=C12

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4755069 0.72
SCHEMBL18986300 0.62
SCHEMBL17221557 0.62
SCHEMBL8329529 0.62
SCHEMBL7409317 0.61
SCHEMBL7569561 0.61
SCHEMBL4395748 0.61
SCHEMBL6234127 0.60
SCHEMBL29568847 0.60
SCHEMBL11769613 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3959211-A1 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE COMPOUNDS Bayer Aktiengesellschaft (DE) 2022-03-02 EP claimed
EP-3959212-A1 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE COMPOUNDS Bayer Aktiengesellschaft (DE) 2022-03-02 EP claimed
EP-3958865-A1 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES Bayer Aktiengesellschaft (DE) 2022-03-02 EP claimed
EP-3250567-A1 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES Bayer Pharma Aktiengesellschaft (DE) 2017-12-06 EP claimed
WO-2016120196-A1 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2016-08-04 WO claimed
WO-2013130660-A1 AMIDES AS PIM INHIBITORS AMGEN INC. (US) 2013-09-06 WO claimed
WO-2008119999-A1 THERAPEUTIC AGENTS ASTRAZENECA AB (SE) 2008-10-09 WO claimed
EP-1973910-A1 PYRROLO Ý3,2-C¨PYRIDINE-4-ONE 2-INDOLINONE PROTEIN KINASE INHIBITORS Shanghai Hengrui Pharmaceutical Co. Ltd. (CN) 2008-10-01 EP claimed
WO-2007085188-A1 PYRROLO [3,2-C] PYRIDINE-4-ONE 2-INDOLINONE PROTEIN KINASE INHIBITORS SHANGHAI HENGRUI PHARMACEUTICAL CO. LTD. (CN) 2007-08-02 WO claimed
US-12565496-B2 Substituted 1H-pyrrolo[3,2-b]pyridine compounds and methods of use thereof BAYER AKTIENGESELLSCHAFT (DE) 2026-03-03 US disclosed
EP-3959211-B1 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE COMPOUNDS BAYER AG (DE) 2026-02-18 EP disclosed
EP-3959211-B1 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE COMPOUNDS BAYER AG (DE) 2026-02-18 EP disclosed
EP-3958865-B1 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES BAYER AG (DE) 2025-12-10 EP disclosed
US-12403135-B2 4H-pyrrolo[3,2-c]pyridin-4-one derivatives BAYER AKTIENGESELLSCHAFT (DE) 2025-09-02 US disclosed
EP-1572693-A1 MITOGEN ACTIVATED PROTEIN KINASE-ACTIVATED PROTEIN KINASE-2 INHIBITING COMPOUNDS Pharmacia Corporation (US) 2005-09-14 EP disclosed
WO-2004058762-A1 MITOGEN ACTIVATED PROTEIN KINASE-ACTIVATED PROTEIN KINASE-2 INHIBITING COMPOUNDS PHARMACIA CORPORATION (US) 2004-07-15 WO disclosed
EP-0729470-B1 HERBICIDAL PYRROLOPYRIDINE COMPOUNDS ZENECA LTD (GB) 1999-05-12 EP disclosed
EP-0729470-A1 HERBICIDAL PYRROLOPYRIDINE COMPOUNDS ZENECA LIMITED (GB) 1996-09-04 EP disclosed
US-5451566-A PREEMERGENCE AND POSTEMERGENCE HERBICIDES ZENECA LIMITED (GB) 1995-09-19 US disclosed
WO-1995014019-A1 HERBICIDAL PYRROLOPYRIDINE COMPOUNDS ZENECA LIMITED (GB) 1995-05-26 WO disclosed