⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721785 | 0.72 | — | — | |
| SCHEMBL13740193 | 0.65 | — | — | |
| SCHEMBL324918 | 0.61 | — | — | |
| SCHEMBL17221557 | 0.61 | — | — | |
| SCHEMBL3754347 | 0.61 | — | — | |
| SCHEMBL219146 | 0.57 | — | — | |
| SCHEMBL8329529 | 0.56 | — | — | |
| SCHEMBL7569561 | 0.56 | — | — | |
| SCHEMBL27459227 | 0.56 | — | — | |
| SCHEMBL7409317 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055016-A1 | GPR52 MODULATOR COMPOUNDS | Heptares Therapeutics Limited (GB) | 2022-09-14 | — | — | EP | claimed |
| EP-1896476-A2 | NOVEL PYRAZOLOPYRIMIDINONE DERIVATIVES | Orchid Research Laboratories Limited (IN) | 2008-03-12 | — | — | EP | claimed |
| WO-2007000655-A2 | NOVEL PYRAZOLOPYRIMIDINONE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-04 | — | — | WO | claimed |
| WO-2025133395-A1 | BICYCLIC (HETERO)ARYLENE WRN INHIBITORY COMPOUNDS | FORX THERAPEUTICS AG (CH) | 2025-06-26 | — | — | WO | disclosed |
| EP-3892621-B1 | HALOALLYLAMINE COMPOUNDS AND APPLICATION THEREOF | TRANSTHERA SCIENCES NANJING INC (CN) | 2024-09-18 | — | — | EP | disclosed |
| US-20230002374-A1 | GPR52 MODULATOR COMPOUNDS | NXERA PHARMA UK LIMITED (GB) | 2023-01-05 | — | — | US | disclosed |
| WO-2020143763-A1 | HALOALLYLAMINE COMPOUNDS AND APPLICATION THEREOF | 南京药捷安康生物科技有限公司 | 2020-07-16 | — | — | WO | disclosed |
| US-20200102316-A1 | 1,5-DIHYDRO-4H-PYRAZOLO[3,4-D]PYRIMIDIN-4-ONES AND 1,5-DIHYDRO-4H-PYRAZOLO[4,3-C]PYRIDIN-4-ONES AS PDE1 INHIBITORS | H. LUNDBECK A/S (DK) | 2020-04-02 | — | — | US | disclosed |