SCHEMBL472194

SCHEMBL472194

C=CC(=O)OCCOC(C)OCC

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.52
ALDH1A1 P00352 6/20 0.52
TP53 P04637 3/20 0.52
HIF1A Q16665 3/20 0.52
HSD17B10 Q99714 1/20 0.52
HPGD P15428 1/20 0.52
THRB P10828 5/20 0.47
CYP3A4 P08684 2/20 0.47
LMNA P02545 1/20 0.43
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ATM Q13315 1/20 0.33
HCAR2 Q8TDS4 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11329528 0.95 TSHR (0.61) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL32689960 0.93 TSHR (0.59) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL7771147 0.89 TSHR (0.56) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL15495137 0.87 TSHR (0.70) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL22829484 0.87 TSHR (0.70) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL19881815 0.85 TSHR (0.61) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL2455964 0.84 TSHR (0.50) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL21768581 0.84 TSHR (0.50) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL3666306 0.84 TSHR (0.53) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL668385 0.82 TSHR (0.52) TSHRALDH1A1TP53HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5910858-A Retroreflective sheeting with coated back surface MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-06-08 US claimed
EP-0426359-B1 Reclosable mechanical fastener based on a composite article MINNESOTA MINING & MFG (US) 1996-07-10 EP claimed
EP-0469196-B1 Terpolymer flocculants S N F (FR) 1995-10-11 EP claimed
US-5316849-A Reclosable mechanical fastener based on a composite article MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-05-31 US claimed
US-5196266-A Cured addition polymer layer MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-03-23 US claimed
EP-0426359-A2 Reclosable mechanical fastener based on a composite article MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-05-08 EP claimed
JP-4149280-A None JP disclosed
EP-4245538-A2 TEXTURED PRODUCTS Sappi North America, Inc. (US) 2023-09-20 EP disclosed
EP-3178653-B1 TEXTURED PRODUCTS SAPPI NORTH AMERICA INC (US) 2023-08-16 EP disclosed
US-11028281-B2 Free radical polymerizable water-based inkjet compositions SUN CHEMICAL CORPORATION (US) 2021-06-08 US disclosed
US-20190264054-A1 FREE RADICAL POLYMERIZABLE WATER-BASED INKJET COMPOSITIONS SUN CHEMICAL CORPORATION (US) 2019-08-29 US disclosed
US-10350819-B2 Release webs and textured products SAPPI NORTH AMERICA, INC. (US) 2019-07-16 US disclosed
EP-3491081-A1 FREE RADICAL POLYMERIZABLE WATER-BASED INKJET COMPOSITIONS Sun Chemical Corporation (US) 2019-06-05 EP disclosed
US-4963471-A MIXTURE OF FLUORINATED BINDER, UNSATURATED LIQUID MONOMER PLASTICIZER, PHOTOINITIATOR E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-16 US disclosed
EP-0382420-A2 Microstructure-bearing composite plastic articles and method of making MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-08-16 EP disclosed
US-4906424-A Reaction injection molding of ceramic or metallic greenbodies HOECHST CELANESE CORP. (US) 1990-03-06 US disclosed
WO-1989007583-A1 REACTION INJECTION MOLDING OF CERAMIC GREENBODIES HOECHST CELANESE CORPORATION (US) 1989-08-24 WO disclosed
US-4826937-A IMPACT STRENGTH, HEAT RESISTANCE ARCO CHEMICAL TECHNOLOGY, INC. (US) 1989-05-02 US disclosed
US-4696978-A BLEND OF ACRYLIC ESTER POLYMER WITH CROSSLINKED ACRYLIC ESTER-MALEIMIDE COPOLYMER ATLANTIC RICHFIELD COMPANY (US) 1987-09-29 US disclosed
EP-0234766-A2 Modified acrylic polymers ARCO Chemical Technology, L.P. (US) 1987-09-02 EP disclosed