Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.34 |
| ▸ | KDM1A | O60341 | 6/20 | 0.33 |
| ▸ | F10 | P00742 | 5/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721962 | 1.00 | ACACB (0.34) | ACACBKDM1AF10F2IDH1 | |
| SCHEMBL4721691 | 0.92 | F10 (0.38) | F10F2 | |
| SCHEMBL4721689 | 0.92 | F10 (0.38) | F10F2 | |
| SCHEMBL4724293 | 0.92 | F10 (0.38) | F10F2 | |
| SCHEMBL4721664 | 0.90 | F10 (0.35) | F10F2CXCR3 | |
| SCHEMBL4723157 | 0.89 | F10 (0.32) | F10F2CXCR3 | |
| SCHEMBL4724288 | 0.89 | F10 (0.40) | F10F2 | |
| SCHEMBL4722374 | 0.88 | ITGB2 (0.37) | ACACBF10 | |
| SCHEMBL4722251 | 0.88 | ITGB2 (0.37) | ACACBF10 | |
| SCHEMBL4766491 | 0.88 | ITGB2 (0.37) | ACACBF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |