Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.40 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721664 | 0.92 | F10 (0.35) | F10F2MAPTWDR5 | |
| SCHEMBL4723157 | 0.91 | F10 (0.32) | F10F2MAPTWDR5 | |
| SCHEMBL14101709 | 0.91 | F10 (0.39) | F10F2MAPTSLC16A3SLC16A1 | |
| SCHEMBL14101712 | 0.91 | F10 (0.39) | F10F2MAPTSLC16A3SLC16A1 | |
| SCHEMBL4722372 | 0.90 | F10 (0.38) | F10F2MAPTSLC16A3SLC16A1 | |
| SCHEMBL4721689 | 0.90 | F10 (0.38) | F10F2 | |
| SCHEMBL4724293 | 0.90 | F10 (0.38) | F10F2 | |
| SCHEMBL4723688 | 0.90 | S1PR1 (0.35) | F10F2WDR5 | |
| SCHEMBL4763492 | 0.90 | F10 (0.34) | F10F2MAPT | |
| SCHEMBL4721691 | 0.90 | F10 (0.38) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |