SCHEMBL472225

SCHEMBL472225

C=C(C)C(=O)NCN1C(=O)c2ccccc2C1=O

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
RPS6KA2 Q15349 5/20 0.47
CA12 O43570 1/20 0.46
CA9 Q16790 1/20 0.46
KDM4E B2RXH2 1/20 0.44
MAPT P10636 1/20 0.44
RAB9A P51151 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
MAPK1 P28482 1/20 0.44
HSD17B10 Q99714 1/20 0.44
POLB P06746 1/20 0.43
HPGD P15428 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8368218 0.76 CA12 (0.60) ALDH1A1CA12CA9KDM4EMAPT
SCHEMBL2808070 0.75 NPSR1 (0.48) ALDH1A1RPS6KA2CA12CA9KDM4E
SCHEMBL9713942 0.75 ALDH1A1 (0.39) ALDH1A1RPS6KA2CA12CA9RAB9A
SCHEMBL761531 0.74 ALDH1A1 (0.56) ALDH1A1CA12CA9NPSR1HSD17B10
SCHEMBL10278735 0.73 GAA (0.36) ALDH1A1NPSR1POLBHPGDMEN1
SCHEMBL1274905 0.72 ALDH1A1 (1.00) ALDH1A1CA12CA9KDM4EMAPT
SCHEMBL30501207 0.71 RPS6KA2 (0.59) ALDH1A1RPS6KA2CA12CA9KDM4E
SCHEMBL19818182 0.71 RPS6KA2 (0.59) ALDH1A1RPS6KA2CA12CA9KDM4E
SCHEMBL9430660 0.71 MAPK1 (0.42) ALDH1A1RPS6KA2CA12CA9MAPT
Ethylene SCHEMBL9096059 0.70 ALDH1A1 (0.70) ALDH1A1CA12CA9KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240166922-A1 RUBBERIZED ASPHALT COMPOSITION WITH ACRYLIC COPOLYMER BASF SE (DE) 2024-05-23 US claimed
EP-4314164-A1 RUBBERIZED ASPHALT COMPOSITION WITH ACRYLIC COPOLYMER BASF SE (DE) 2024-02-07 EP claimed
EP-2042305-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2011-01-12 EP claimed
US-6190825-B1 N-(P-AMINOSULFONYL)PHENYL-SUBSTITUTED AGFA-GEVAERT N.V. (BE) 2001-02-20 US claimed
US-5549807-A Thermoplastic composites formed by electropolymerization of N-substituted methacrylamide monomers THE UNIVERSITY OF CONNECTICUT (US) 1996-08-27 US claimed
US-5238542-A Onto electrically conductive filler THE UNIVERSITY OF CONNECTICUT (US) 1993-08-24 US claimed
US-20240166922-A1 RUBBERIZED ASPHALT COMPOSITION WITH ACRYLIC COPOLYMER BASF SE (DE) 2024-05-23 US disclosed
EP-4314164-A1 RUBBERIZED ASPHALT COMPOSITION WITH ACRYLIC COPOLYMER BASF SE (DE) 2024-02-07 EP disclosed
EP-1964893-B2 Ink composition, inkjet recording method, printed material, and ink set FUJIFILM CORP (JP) 2021-11-24 EP disclosed
EP-1964893-B1 Ink composition, inkjet recording method, printed material, and ink set FUJIFILM CORP (JP) 2018-01-24 EP disclosed
EP-2598551-B1 RADIATION CURABLE AQUEOUS COMPOSITIONS ALLNEX Belgium SA (BE) 2017-06-21 EP disclosed
US-9169381-B2 Radiation curable aqueous compositions ALLNEX BELGIUM S.A. (BE) 2015-10-27 US disclosed
US-8729071-B2 Iminothiadiazine dioxide compounds as BACE inhibitors, compositions and their use MERCK SHARP & DOHME CORP. (US) 2014-05-20 US disclosed
EP-0602377-A1 Polymers containing N,N-disubstituted sulfonamide side groups and their use in radiation-sensitive compositions HOECHST AKTIENGESELLSCHAFT (DE) 1994-06-22 EP disclosed
US-5264533-A Acrylate resins as hot melt adhesives BASF AKTIENGESELLSCHAFT (DE) 1993-11-23 US disclosed
EP-0346734-B1 Derivatives of benzophenone and their preparation BASF AG (DE) 1993-11-03 EP disclosed
EP-0377199-B1 UV-CROSS-LINKABLE COMPOSITIONS BASED ON POLYMERS OF (METH)ACRYLIC ESTERS BASF Aktiengesellschaft (DE) 1993-05-26 EP disclosed
EP-0448741-A1 UV-curable compositions based on polymers of (meth)acrylic esters BASF Aktiengesellschaft (DE) 1991-10-02 EP disclosed
EP-0346734-A2 Derivatives of benzophenone and their preparation BASF Aktiengesellschaft (DE) 1989-12-20 EP disclosed
EP-0339522-A2 By UV-radiation crosslinkable composition for the preparation of adhering coatings BASF Aktiengesellschaft (DE) 1989-11-02 EP disclosed