Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 12/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 11/20 | 0.43 |
| ▸ | MBTD1 | Q05BQ5 | 5/20 | 0.43 |
| ▸ | TP53BP1 | Q12888 | 3/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3314168 | 0.87 | L3MBTL3 (0.47) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL4717748 | 0.85 | PARP1 (0.39) | CYP3A4CYP2D6CYP2C19LRRK2L3MBTL3 | |
| SCHEMBL3279492 | 0.85 | L3MBTL3 (0.50) | CYP2D6CYP2C19LRRK2L3MBTL3L3MBTL1 | |
| SCHEMBL4720815 | 0.83 | L3MBTL3 (0.41) | CYP3A4CYP2D6CYP2C19LRRK2L3MBTL3 | |
| SCHEMBL4722465 | 0.78 | CCR3 (0.41) | CYP3A4CYP2D6CYP2C19LRRK2L3MBTL3 | |
| SCHEMBL3314680 | 0.78 | CCR3 (0.41) | CYP3A4CYP2D6CYP2C19LRRK2L3MBTL3 | |
| SCHEMBL4862660 | 0.78 | HRH4 (0.44) | L3MBTL3L3MBTL1MBTD1HRH3 | |
| SCHEMBL4718739 | 0.78 | PARP1 (0.35) | KMT2APARP1 | |
| SCHEMBL4594198 | 0.77 | PDE3B (0.38) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL4862674 | 0.76 | L3MBTL3 (0.38) | CYP3A4L3MBTL3L3MBTL1MBTD1TP53BP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558600-B1 | SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-05-07 | — | — | EP | claimed |