Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722353 | 1.00 | TSHR (0.40) | TSHRNPC1RAB9ATP53KDM4E | |
| SCHEMBL891499 | 0.81 | ALDH1A1 (0.41) | TSHRKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL891343 | 0.81 | ALDH1A1 (0.41) | TSHRKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2432464 | 0.81 | ALDH1A1 (0.41) | TSHRKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1148 | 0.77 | TSHR (0.61) | TSHRTP53MEN1KMT2APTGS1 | |
| SCHEMBL29487262 | 0.77 | TSHR (0.61) | TSHRTP53MEN1KMT2APTGS1 | |
| P-Cymene SCHEMBL23296191 | 0.71 | TP53 (0.54) | TSHRTP53PTGS1PTGS2LMNA | |
| SCHEMBL3484487 | 0.70 | TP53 (0.60) | TSHRNPC1RAB9ATP53MEN1 | |
| SCHEMBL97559 | 0.70 | TP53 (0.60) | TSHRNPC1RAB9ATP53MEN1 | |
| SCHEMBL286217 | 0.70 | TP53 (0.60) | TSHRNPC1RAB9ATP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080247966-A1 | Compositions and Methods to Counteract Oral Malodour | GIVAUDAN SA (CH) | 2008-10-09 | — | — | US | disclosed |
| EP-1919566-A1 | COMPOSITIONS AND METHODS TO COUNTERACT ORAL MALODOUR | Givaudan SA (CH) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007025401-A1 | COMPOSITIONS AND METHODS TO COUNTERACT ORAL MALODOUR | GIVAUDAN SA (CH) | 2007-03-08 | — | — | WO | disclosed |