Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | MDM4 | O15151 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722547 | 1.00 | KMT2A (0.35) | KMT2AMEN1USP2LMNAMAPT | |
| SCHEMBL4721094 | 0.96 | F10 (0.33) | KMT2AKDM4EF10F2 | |
| SCHEMBL4721098 | 0.96 | F10 (0.33) | KMT2AKDM4EF10F2 | |
| SCHEMBL4720367 | 0.96 | F10 (0.33) | KMT2AKDM4EF10F2 | |
| SCHEMBL4720373 | 0.96 | F10 (0.33) | KMT2AKDM4EF10F2 | |
| SCHEMBL4720061 | 0.95 | F10 (0.33) | KMT2AMEN1LMNAF10F2 | |
| SCHEMBL4720066 | 0.95 | F10 (0.33) | KMT2AMEN1LMNAF10F2 | |
| SCHEMBL4724067 | 0.92 | KMT2A (0.34) | KMT2AMEN1MAPTKDM4EOPRM1 | |
| SCHEMBL4724059 | 0.92 | KMT2A (0.34) | KMT2AMEN1MAPTKDM4EOPRM1 | |
| SCHEMBL14101989 | 0.92 | ADRA1D (0.39) | KMT2AMEN1USP2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |