Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4719155 | 0.93 | GAA (0.52) | SMN1; SMN2GAALMNAALDH1A1NPSR1 | |
| SCHEMBL4724425 | 0.90 | NPSR1 (0.56) | SMN1; SMN2GAALMNAALDH1A1NPSR1 | |
| SCHEMBL4721772 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2GAALMNAALDH1A1NPSR1 | |
| SCHEMBL4718962 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2GAALMNAALDH1A1NPSR1 | |
| SCHEMBL4766617 | 0.83 | MAPT (0.69) | SMN1; SMN2GAALMNAALDH1A1NPSR1 | |
| SCHEMBL4721916 | 0.80 | ALDH1A1 (0.45) | SMN1; SMN2GAALMNAALDH1A1MAPT | |
| SCHEMBL4722858 | 0.78 | NPSR1 (0.59) | GAALMNAALDH1A1NPSR1PDE4A | |
| SCHEMBL4723099 | 0.78 | ALDH1A1 (0.43) | SMN1; SMN2GAALMNAALDH1A1MAPT | |
| SCHEMBL4722132 | 0.78 | SMN1; SMN2 (0.74) | SMN1; SMN2GAALMNAALDH1A1NPSR1 | |
| SCHEMBL4723172 | 0.78 | GAA (0.57) | SMN1; SMN2GAALMNAALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |