SCHEMBL4722936

SCHEMBL4722936

CN(C)C(=O)N1C=CC=CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27666696 0.82
SCHEMBL28761562 0.81
SCHEMBL4722778 0.81
SCHEMBL27685582 0.80 P2RX4 (0.36)
SCHEMBL27685594 0.79 HTR1A (0.39)
SCHEMBL4788208 0.76
Cytosine SCHEMBL7095941 0.76
SCHEMBL8865924 0.75
SCHEMBL4761631 0.75 KDM4E (0.32)
SCHEMBL5248947 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109154093-A Electrolytic nickel (alloy) plating liquid 日本高纯度化学株式会社 2019-01-04 CN claimed
EP-1963320-A1 PYRROLOPYRIDINE KINASE INHIBITING COMPOUNDS OSI Pharmaceuticals, Inc. (US) 2008-09-03 EP claimed
WO-2007067537-A1 PYRROLOPYRIDINE KINASE INHIBITING COMPOUNDS OSI PHARMACEUTICALS, INC. (US) 2007-06-14 WO claimed
CN-109154093-A Electrolytic nickel (alloy) plating liquid 日本高纯度化学株式会社 2019-01-04 CN disclosed
EP-1963320-A1 PYRROLOPYRIDINE KINASE INHIBITING COMPOUNDS OSI Pharmaceuticals, Inc. (US) 2008-09-03 EP disclosed
WO-2007067537-A1 PYRROLOPYRIDINE KINASE INHIBITING COMPOUNDS OSI PHARMACEUTICALS, INC. (US) 2007-06-14 WO disclosed