⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7007431 | 0.73 | — | — | |
| SCHEMBL7555974 | 0.73 | — | — | |
| SCHEMBL9698528 | 0.73 | — | — | |
| SCHEMBL7158758 | 0.67 | ALDH1A1 (0.31) | — | |
| SCHEMBL16369338 | 0.65 | — | — | |
| SCHEMBL685459 | 0.65 | — | — | |
| SCHEMBL15256705 | 0.65 | — | — | |
| SCHEMBL11240395 | 0.64 | ALDH1A1 (0.40) | — | |
| SCHEMBL3956349 | 0.62 | — | — | |
| SCHEMBL6117195 | 0.62 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189176-A1 | ONE-SIDED PROTECTED 2,2 -DIHYDROXY BIARYLS AND ELECTROCHEMICAL METHOD FOR THE PRODUCTION THEREOF | Evonik Degussa GmbH (DE) | 2017-07-12 | — | — | EP | claimed |
| WO-2016034326-A1 | ONE-SIDED PROTECTED 2,2 -DIHYDROXY BIARYLS AND ELECTROCHEMICAL METHOD FOR THE PRODUCTION THEREOF | EVONIK DEGUSSA GMBH (DE) | 2016-03-10 | — | — | WO | claimed |
| EP-3189176-A1 | ONE-SIDED PROTECTED 2,2 -DIHYDROXY BIARYLS AND ELECTROCHEMICAL METHOD FOR THE PRODUCTION THEREOF | Evonik Degussa GmbH (DE) | 2017-07-12 | — | — | EP | disclosed |
| WO-2016034326-A1 | ONE-SIDED PROTECTED 2,2 -DIHYDROXY BIARYLS AND ELECTROCHEMICAL METHOD FOR THE PRODUCTION THEREOF | EVONIK DEGUSSA GMBH (DE) | 2016-03-10 | — | — | WO | disclosed |
| EP-1928844-A2 | BIS-ARYL AMIDE COMPOUNDS AND METHODS OF USE | Amgen, Inc (US) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007022380-A2 | BIS-ARYL AMIDE COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2007-02-22 | — | — | WO | disclosed |
| US-7074780-B2 | Substituted phenylcyclohexanecarboxamides and their use | BAYER AKTIENGESELLSCHAFT (DE) | 2006-07-11 | — | — | US | disclosed |
| US-20040122004-A1 | Substituted phenylcyclohexanecarboxamides and their use | BAYER AKTIENGESELLSCHAFT (DE) | 2004-06-24 | — | — | US | disclosed |
| US-5705659-A | Intermediates for the synthesis of 16-phenoxy-prostatrienoic acid derivatives and a preparing method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1998-01-06 | — | — | US | disclosed |