Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | GAK | O14976 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4723258 | 0.92 | HTT (0.42) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL4724315 | 0.91 | MEN1 (0.45) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL4723995 | 0.91 | GAA (0.50) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL4722685 | 0.88 | MEN1 (0.46) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL4723860 | 0.88 | ADRA1D (0.42) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL4723078 | 0.83 | CYP1A2 (0.41) | MEN1KMT2AMAPTMAPK1LMNA | |
| SCHEMBL4724040 | 0.83 | CYP1A2 (0.44) | MEN1KMT2AMAPTMAPK1CYP1A2 | |
| SCHEMBL4722912 | 0.82 | MAPT (0.49) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL4722409 | 0.81 | MAPT (0.53) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL4719751 | 0.79 | ADRA1D (0.44) | MEN1KMT2AMAPTTDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |