⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1101400 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL29471655 | 0.81 | — | — | |
| SCHEMBL3949066 | 0.79 | — | — | |
| SCHEMBL1042812 | 0.76 | — | — | |
| SCHEMBL30675167 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL29508586 | 0.74 | — | — | |
| SCHEMBL30532723 | 0.74 | — | — | |
| Hydrazine SCHEMBL28121587 | 0.73 | — | — | |
| SCHEMBL861254 | 0.70 | — | — | |
| Chloroform SCHEMBL27610928 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004625-A2 | C-MET PROTEIN KINASE INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | Vertex Pharmaceuticals Incorporated (US) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007111904-A2 | C-MET PROTEIN KINASE INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2007-10-04 | — | — | WO | disclosed |