SCHEMBL47235

SCHEMBL47235

C(=C/C=N/c1ccccc1)\C=C\Nc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 1.00
KDM4E B2RXH2 3/20 0.65
CYP2D6 P10635 2/20 0.65
CYP1A2 P05177 1/20 0.65
CYP2C9 P11712 1/20 0.65
CYP2C19 P33261 1/20 0.65
ALDH1A1 P00352 6/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 1/20 0.37
NFKB1 P19838 1/20 0.37
RAB9A P51151 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
MEN1 O00255 6/20 0.35
MAPT P10636 5/20 0.35
MAPK1 P28482 4/20 0.35
L3MBTL1 Q9Y468 3/20 0.35
TDP1 Q9NUW8 2/20 0.34
CYP1A1 P04798 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13790517 1.00 KMT2A (1.00) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
SCHEMBL27289392 1.00 KMT2A (1.00) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
SCHEMBL530958 1.00 KMT2A (1.00) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
SCHEMBL13790322 1.00 KMT2A (1.00) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
SCHEMBL530957 1.00 KMT2A (1.00) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
SCHEMBL13223423 1.00 KMT2A (1.00) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
Hydrochloric Acid SCHEMBL42417 0.98 KMT2A (0.96) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
Hydrochloric Acid SCHEMBL2379569 0.98 KMT2A (0.96) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
Hydrochloric Acid SCHEMBL2918479 0.98 KMT2A (0.96) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
Hydrochloric Acid SCHEMBL316433 0.98 KMT2A (0.96) KMT2AKDM4ECYP2D6CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240358862-A1 Synthesis Method and Application of a Near-infrared Probe GGa-ICG specific binding to PSCA GUANGZHOU SHIYUN BIOTECHNOLOGY CO LTD (CN) 2024-10-31 US claimed
EP-4265611-A2 SYNTHESIS METHOD AND APPLICATION OF PSCA-SPECIFIC NEAR-INFRARED PROBE GGA-ICG Guangzhou Shiwen Biotechnology Co., Ltd. (CN) 2023-10-25 EP claimed
EP-3383436-B1 AN IMPROVED PROCESS FOR THE PREPARATION OF INDOCYANINE GREEN DISHMAN CARBOGEN AMCIS LTD (IN) 2023-08-30 EP claimed
US-10287436-B2 Process for the preparation of indocyanine green DISHMAN CARBOGEN AMCIS LIMITED (IN) 2019-05-14 US claimed
US-20180346728-A1 PROCESS FOR THE PREPARATION OF INDOCYANINE GREEN DISHMAN PHARMACEUTICALS AND CHEMICALS LIMITED (IN) 2018-12-06 US claimed
US-20260117071-A1 ICG LIPID DERIVATIVE, AND LIPID MICROPARTICLES EACH CONTAINING SAME NATIONAL UNIVERSITY CORPORATION HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE (JP) 2026-04-30 US disclosed
EP-4516797-A1 ICG LIPID DERIVATIVE, AND LIPID MICROPARTICLES EACH CONTAINING SAME Eisai R&D Management Co., Ltd. (JP) 2025-03-05 EP disclosed
US-20240358862-A1 Synthesis Method and Application of a Near-infrared Probe GGa-ICG specific binding to PSCA GUANGZHOU SHIYUN BIOTECHNOLOGY CO LTD (CN) 2024-10-31 US disclosed
WO-2023210645-A1 ICG LIPID DERIVATIVE, AND LIPID MICROPARTICLES EACH CONTAINING SAME エーザイ・アール・アンド・ディー・マネジメント株式会社 2023-11-02 WO disclosed
WO-2023210645-A1 ICG LIPID DERIVATIVE, AND LIPID MICROPARTICLES EACH CONTAINING SAME エーザイ・アール・アンド・ディー・マネジメント株式会社 2023-11-02 WO disclosed
EP-4265611-A2 SYNTHESIS METHOD AND APPLICATION OF PSCA-SPECIFIC NEAR-INFRARED PROBE GGA-ICG Guangzhou Shiwen Biotechnology Co., Ltd. (CN) 2023-10-25 EP disclosed
EP-3383436-B1 AN IMPROVED PROCESS FOR THE PREPARATION OF INDOCYANINE GREEN DISHMAN CARBOGEN AMCIS LTD (IN) 2023-08-30 EP disclosed
US-7473415-B2 Near infrared fluorescent contrast agent and method for fluorescence imaging FUJI PHOTO FILM CO., LTD. (JP) 2009-01-06 US disclosed
US-7473415-B2 Near infrared fluorescent contrast agent and method for fluorescence imaging FUJI PHOTO FILM CO., LTD. (JP) 2009-01-06 US disclosed
EP-1480683-B1 NEAR INFRARED FLUORESCENT CONTRAST AGENT AND METHOD FOR FLUORESCENCE IMAGING FUJIFILM CORP (JP) 2008-05-14 EP disclosed
US-20080090174-A1 Novel Oxonol Dye Compounds and Optical Information Recording Medium FUJIFILM CORPORATION (JP) 2008-04-17 US disclosed
US-20080090174-A1 Novel Oxonol Dye Compounds and Optical Information Recording Medium FUJIFILM CORPORATION (JP) 2008-04-17 US disclosed
US-7183422-B2 Oxonol compound and process for producing the compound FUJI PHOTO FILM CO., LTD. (JP) 2007-02-27 US disclosed
US-7183422-B2 Oxonol compound and process for producing the compound FUJI PHOTO FILM CO., LTD. (JP) 2007-02-27 US disclosed
US-4362800-A CYANINE DYES FUJI PHOTO FILM CO., LTD. (JP) 1982-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080090174-A1 Novel Oxonol Dye Compounds and Optical Information Recording Medium KCNB1, KCNMB1, HCN2 KMT2A 2987/4885KDM4E 3134/4885CYP2D6 1646/4885
US-20260117071-A1 ICG LIPID DERIVATIVE, AND LIPID MICROPARTICLES EACH CONTAINING SAME LDLR, CHMP4B, CETP KMT2A 3479/4885KDM4E 1874/4885CYP2D6 421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.