Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4719420 | 0.91 | GPR119 (0.61) | GPR119CYP2C9KCNH2CDK2FLT3 | |
| SCHEMBL4723041 | 0.91 | GPR119 (0.55) | GPR119CYP2C9KCNH2ACACBCDK2 | |
| SCHEMBL4721651 | 0.91 | GPR119 (0.60) | GPR119CYP2C9KCNH2CDK2FLT3 | |
| SCHEMBL4723164 | 0.88 | GPR119 (0.58) | GPR119CYP2C9KCNH2ACACB | |
| SCHEMBL4718809 | 0.88 | GPR119 (0.57) | GPR119CYP2C9KCNH2CDK2FLT3 | |
| SCHEMBL4721322 | 0.88 | GPR119 (0.58) | GPR119CYP2C9KCNH2CDK2FLT3 | |
| SCHEMBL386785 | 0.88 | GPR119 (0.80) | GPR119CYP2C9KCNH2 | |
| SCHEMBL4718883 | 0.85 | GPR119 (0.53) | GPR119CYP2C9ACACBCDK2FLT3 | |
| SCHEMBL4718845 | 0.85 | GPR119 (0.63) | GPR119CYP2C9ACACBCDK2FLT3 | |
| SCHEMBL4720771 | 0.85 | GPR119 (0.48) | GPR119CYP2C9ACACBCDK2FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756084-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES AS MODULATORS OF METABOLISM AND THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARM INC (US) | 2008-11-26 | — | — | EP | claimed |