SCHEMBL4724028

SCHEMBL4724028

Cc1c(CC(=O)O)c2cccnc2n1CC(=O)c1ccc(S(C)(=O)=O)cc1

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2922874 0.89 PTGDR2 (0.59) PTGDR2
Qav680 SCHEMBL1941180 0.85 PTGDR2 (1.00) PTGDR2
Qav680 SCHEMBL29376454 0.85 PTGDR2 (1.00) PTGDR2
SCHEMBL1940435 0.82 PTGDR2 (1.00) PTGDR2
SCHEMBL1939869 0.81 PTGDR2 (0.85) PTGDR2
SCHEMBL1940463 0.78 PTGDR2 (0.79) PTGDR2
SCHEMBL1940837 0.78 PTGDR2 (1.00) PTGDR2
SCHEMBL1939894 0.77 PTGDR2 (1.00) PTGDR2
Fevipiprant SCHEMBL29355753 0.76 PTGDR2 (1.00) PTGDR2
Fevipiprant SCHEMBL1940595 0.76 PTGDR2 (1.00) PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1960398-A1 ARYL ACETIC ACID AND ESTER DERIVATIVES AND THEIR USES AS ANTIINFLAMMATORY Novartis AG (CH) 2008-08-27 EP disclosed
WO-2007065683-A1 ARYL ACETIC ACID AND ESTER DERIVATIVES AND THEIR USES AS ANTIINFLAMMATORY NOVARTIS AG (CH) 2007-06-14 WO disclosed