Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.50 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4723882 | 0.85 | ALDH1A1 (0.59) | SMN1; SMN2GAAHTTMAPTHTR6 | |
| SCHEMBL4718984 | 0.83 | GAA (0.60) | SMN1; SMN2GAAHTTMAPTHTR6 | |
| SCHEMBL4722046 | 0.81 | GAA (0.74) | SMN1; SMN2GAAHTTMAPTHTR6 | |
| SCHEMBL4722553 | 0.81 | GAA (0.58) | SMN1; SMN2GAAHTTMAPTHTR6 | |
| SCHEMBL4718996 | 0.80 | GAA (0.55) | SMN1; SMN2GAAHTTMAPTHTR6 | |
| SCHEMBL4724499 | 0.80 | GAA (0.54) | SMN1; SMN2GAAHTTMAPTHTR6 | |
| SCHEMBL4721879 | 0.80 | GAA (0.54) | SMN1; SMN2GAAHTTMAPTHTR6 | |
| SCHEMBL4724257 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2GAAHTTMAPTHTR6 | |
| SCHEMBL4722217 | 0.79 | GAA (0.54) | SMN1; SMN2GAAHTTMAPTHTR6 | |
| SCHEMBL4719934 | 0.79 | HTT (0.56) | SMN1; SMN2GAAHTTMAPTHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |