Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ1 | P51787 | 8/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4723829 | 0.87 | CNR2 (0.68) | KCNQ1CNR2SMN1; SMN2LMNAMAPT | |
| SCHEMBL3144602 | 0.86 | KCNQ1 (0.55) | KCNQ1CNR2SMN1; SMN2LMNAMAPT | |
| SCHEMBL13524280 | 0.86 | KCNQ1 (0.55) | KCNQ1CNR2SMN1; SMN2LMNAMAPT | |
| SCHEMBL13256798 | 0.83 | KCNQ1 (0.65) | KCNQ1CNR2SMN1; SMN2LMNAMAPT | |
| SCHEMBL2575773 | 0.80 | KDM4E (0.66) | SMN1; SMN2LMNAMAPTALDH1A1HSD17B10 | |
| SCHEMBL7474949 | 0.80 | TRPV1 (0.50) | KCNQ1CNR2SMN1; SMN2LMNAMAPT | |
| SCHEMBL7474942 | 0.80 | TRPV1 (0.50) | KCNQ1CNR2SMN1; SMN2LMNAMAPT | |
| SCHEMBL19837795 | 0.79 | MEN1 (0.61) | KCNQ1SMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL3140343 | 0.78 | KCNQ1 (0.58) | KCNQ1CNR2SMN1; SMN2LMNAMAPT | |
| SCHEMBL13524070 | 0.78 | KCNQ1 (0.58) | KCNQ1CNR2SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971597-A2 | N-(5-MEMBERED HETEROAROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007070600-A2 | N-(5-MEMBERED HETEROAROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 2007-06-21 | — | — | WO | disclosed |