Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | KCNQ1 | P51787 | 6/20 | 0.60 |
| ▸ | POLB | P06746 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.52 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18029515 | 0.89 | MEN1 (0.57) | MEN1KMT2AMAPK1ALDH1A1ALOX15 | |
| SCHEMBL13524044 | 0.86 | MEN1 (0.62) | MEN1KMT2AMAPK1ALDH1A1ALOX15 | |
| SCHEMBL3143723 | 0.86 | MEN1 (0.62) | MEN1KMT2AMAPK1ALDH1A1ALOX15 | |
| SCHEMBL4723829 | 0.82 | CNR2 (0.68) | MEN1KMT2AALDH1A1HSD17B10KCNQ1 | |
| SCHEMBL13256798 | 0.81 | KCNQ1 (0.65) | MEN1KMT2AALDH1A1HSD17B10KCNQ1 | |
| SCHEMBL4724306 | 0.79 | KCNQ1 (0.55) | MEN1KMT2AALDH1A1HSD17B10KCNQ1 | |
| SCHEMBL13523983 | 0.79 | MEN1 (0.59) | MEN1KMT2AALDH1A1KCNQ1KDM4E | |
| SCHEMBL13524107 | 0.79 | MEN1 (0.59) | MEN1KMT2AALDH1A1KCNQ1KDM4E | |
| SCHEMBL3129451 | 0.79 | MEN1 (0.59) | MEN1KMT2AALDH1A1KCNQ1KDM4E | |
| SCHEMBL3144912 | 0.79 | MEN1 (0.59) | MEN1KMT2AALDH1A1KCNQ1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180037556-A1 | COMPOUNDS AND METHODS FOR INDUCING BROWNING OF WHITE ADIPOSE TISSUE | BEIJING ERAI THERAPEUTICS CO., LTD. (CN) | 2018-02-08 | — | — | US | claimed |
| CN-107635981-B | Compounds and methods for inducing browning of white adipose tissue | 中国科学院广州生物医药与健康研究院 | 2020-08-04 | — | — | CN | disclosed |
| US-20180037556-A1 | COMPOUNDS AND METHODS FOR INDUCING BROWNING OF WHITE ADIPOSE TISSUE | BEIJING ERAI THERAPEUTICS CO., LTD. (CN) | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037556-A1 | COMPOUNDS AND METHODS FOR INDUCING BROWNING OF WHITE ADIPOSE TISSUE | FABP4, LRBA, GPR119 | MEN1 3965/4885KMT2A 2404/4885MAPK1 2199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.