Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13536857 | 0.80 | MAPK1 (0.48) | MEN1CYP3A4ALOX15KMT2AMAPK1 | |
| SCHEMBL28234726 | 0.80 | LMNA (0.43) | — | |
| SCHEMBL2304823 | 0.76 | — | — | |
| SCHEMBL11688603 | 0.76 | MEN1 (0.35) | MEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL19118274 | 0.75 | MEN1 (0.42) | MEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL13536865 | 0.74 | MAPK1 (0.41) | MAPK1 | |
| SCHEMBL12112393 | 0.73 | — | — | |
| SCHEMBL13701664 | 0.73 | — | — | |
| SCHEMBL1517434 | 0.73 | MEN1 (0.36) | MEN1CYP3A4ALOX15KMT2AMAPK1 | |
| SCHEMBL1269883 | 0.73 | LMNA (0.57) | MEN1CYP3A4ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809607-B1 | SULFONYL BENZIMIDAZOLE DERIVATIVES | PFIZER (US) | 2008-12-17 | — | — | EP | disclosed |