Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 8/20 | 0.67 |
| ▸ | AR | P10275 | 5/20 | 0.67 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.67 |
| ▸ | PGR | P06401 | 2/20 | 0.67 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4288507 | 0.80 | NR3C2 (1.00) | NR3C2ARNR3C1PGR | |
| SCHEMBL4290679 | 0.71 | NR3C2 (0.82) | NR3C2ARNR3C1PGR | |
| SCHEMBL4295953 | 0.69 | NR3C2 (0.79) | NR3C2ARNR3C1PGR | |
| SCHEMBL4291243 | 0.65 | NR3C2 (1.00) | NR3C2ARNR3C1PGR | |
| SCHEMBL4289670 | 0.64 | NR3C2 (0.71) | NR3C2ARNR3C1PGR | |
| SCHEMBL4286804 | 0.62 | NR3C2 (0.69) | NR3C2ARNR3C1PGR | |
| SCHEMBL4289607 | 0.62 | NR3C2 (0.68) | NR3C2ARNR3C1PGR | |
| Benzene SCHEMBL27714049 | 0.62 | MAOA (0.46) | — | |
| SCHEMBL4295082 | 0.61 | NR3C2 (0.66) | NR3C2ARNR3C1PGR | |
| SCHEMBL4296030 | 0.60 | NR3C2 (0.69) | NR3C2ARNR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971596-A2 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS MINERALOCORTICOID RECEPTOR LIGANDS | Takeda Pharmaceutical Company Limited (JP) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007077961-A2 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS MINERALOCORTICOID RECEPTOR LIGANDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-07-12 | — | — | WO | disclosed |