Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 8/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4719701 | 0.91 | GAA (0.41) | NPSR1GAAMAPTLMNAALDH1A1 | |
| SCHEMBL4719385 | 0.87 | GAA (0.54) | NPSR1GAAMAPTLMNAALDH1A1 | |
| SCHEMBL4724434 | 0.87 | MEN1 (0.40) | NPSR1GAAMAPTLMNAALDH1A1 | |
| SCHEMBL4718794 | 0.87 | NPSR1 (0.47) | NPSR1GAAMAPTLMNAALDH1A1 | |
| SCHEMBL4722686 | 0.86 | NPSR1 (0.65) | NPSR1GAAMAPTLMNAALDH1A1 | |
| SCHEMBL4722543 | 0.85 | MEN1 (0.43) | NPSR1GAAMAPTLMNAALDH1A1 | |
| SCHEMBL4722439 | 0.83 | MEN1 (0.43) | NPSR1GAAMAPTLMNAALDH1A1 | |
| SCHEMBL4719649 | 0.83 | MEN1 (0.40) | NPSR1GAAMAPTLMNAALDH1A1 | |
| SCHEMBL4723973 | 0.83 | NPSR1 (0.49) | NPSR1GAAMAPTLMNAALDH1A1 | |
| SCHEMBL4721402 | 0.80 | MAPT (0.49) | NPSR1GAAMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |