Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.73 |
| ▸ | MAPT | P10636 | 5/20 | 0.73 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.59 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7341640 | 0.88 | ALDH1A1 (0.71) | ALDH1A1MAPTGAAPKMRXFP1 | |
| SCHEMBL4295545 | 0.88 | ALDH1A1 (0.71) | ALDH1A1MAPTGAAPKMRXFP1 | |
| SCHEMBL4293880 | 0.85 | ALDH1A1 (0.68) | ALDH1A1MAPTGAAPKMRXFP1 | |
| SCHEMBL10652999 | 0.84 | MAPT (0.78) | ALDH1A1MAPTGAAPKMRXFP1 | |
| SCHEMBL4264178 | 0.84 | ALDH1A1 (0.75) | ALDH1A1MAPTGAAPKMRXFP1 | |
| SCHEMBL4291442 | 0.84 | ALDH1A1 (0.75) | ALDH1A1MAPTGAAPKMRXFP1 | |
| SCHEMBL532500 | 0.84 | ALDH1A1 (1.00) | ALDH1A1MAPTGAAPKMRXFP1 | |
| SCHEMBL29550875 | 0.84 | ALDH1A1 (1.00) | ALDH1A1MAPTGAAPKMRXFP1 | |
| SCHEMBL4294026 | 0.84 | ALDH1A1 (0.67) | ALDH1A1MAPTGAAPKMRXFP1 | |
| SCHEMBL532793 | 0.84 | GAA (0.71) | ALDH1A1MAPTGAAPKMRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971596-A2 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS MINERALOCORTICOID RECEPTOR LIGANDS | Takeda Pharmaceutical Company Limited (JP) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007077961-A2 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS MINERALOCORTICOID RECEPTOR LIGANDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-07-12 | — | — | WO | disclosed |