⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4071209 | 0.82 | — | — | |
| SCHEMBL9445541 | 0.78 | — | — | |
| SCHEMBL5248526 | 0.78 | — | — | |
| SCHEMBL27547026 | 0.77 | — | — | |
| SCHEMBL11573696 | 0.76 | — | — | |
| SCHEMBL10458715 | 0.76 | ALOX15 (0.46) | — | |
| SCHEMBL4869307 | 0.75 | — | — | |
| SCHEMBL346429 | 0.75 | — | — | |
| SCHEMBL7711519 | 0.74 | ALOX15 (0.44) | — | |
| SCHEMBL29650682 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963320-A1 | PYRROLOPYRIDINE KINASE INHIBITING COMPOUNDS | OSI Pharmaceuticals, Inc. (US) | 2008-09-03 | — | — | EP | claimed |
| EP-1797054-A2 | ARYL-AMINO SUBSTITUTED PYRROLOPYRIMIDINE MULTI-KINASE INHIBITING COMPOUNDS | OSI Pharmaceuticals, Inc. (US) | 2007-06-20 | — | — | EP | claimed |
| WO-2007067537-A1 | PYRROLOPYRIDINE KINASE INHIBITING COMPOUNDS | OSI PHARMACEUTICALS, INC. (US) | 2007-06-14 | — | — | WO | claimed |
| WO-2006017443-A2 | ARYL-AMINO SUBSTITUTED PYRROLOPYRIMIDINE MULTI-KINASE INHIBITING COMPOUNDS | OSI PHARMACEUTICALS, INC. (US) | 2006-02-16 | — | — | WO | claimed |
| EP-1963320-A1 | PYRROLOPYRIDINE KINASE INHIBITING COMPOUNDS | OSI Pharmaceuticals, Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007067537-A1 | PYRROLOPYRIDINE KINASE INHIBITING COMPOUNDS | OSI PHARMACEUTICALS, INC. (US) | 2007-06-14 | — | — | WO | disclosed |
| WO-1997041128-A1 | 3-PYRAZOLIOMETHYLCEPHEM COMPOUNDS AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-06 | — | — | WO | disclosed |
| EP-0307804-B1 | Cephem compound and a process for preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-11-18 | — | — | EP | disclosed |
| US-4952578-A | Cephem compound and a process for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-28 | — | — | US | disclosed |
| EP-0307804-A2 | Cephem compound and a process for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-03-22 | — | — | EP | disclosed |