Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.44 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1019327 | 0.87 | TAAR1 (0.48) | ALDH1A1CYP2C19HIF1ACYP3A4HPGD | |
| SCHEMBL19670976 | 0.74 | TAAR1 (0.50) | ALDH1A1CYP2C19HIF1ATAAR1MAPKAPK2 | |
| SCHEMBL28330062 | 0.73 | TAAR1 (0.54) | ALDH1A1CYP2C19HIF1ACYP3A4HTT | |
| SCHEMBL9775119 | 0.71 | GAA (0.49) | ALDH1A1CYP2C19HIF1APLOD2PLOD3 | |
| SCHEMBL1850 | 0.70 | CYP2C19 (0.55) | ALDH1A1CYP2C19HIF1ACYP1A2CYP3A4 | |
| SCHEMBL28864314 | 0.70 | TAAR1 (0.50) | ALDH1A1CYP2C19HIF1ACYP1A2CYP3A4 | |
| SCHEMBL1024978 | 0.69 | TAAR1 (0.45) | ALDH1A1CYP2C19HIF1ACYP3A4HTT | |
| SCHEMBL369772 | 0.69 | CYP3A4 (0.58) | ALDH1A1CYP2C19HIF1APLOD2PLOD3 | |
| SCHEMBL295450 | 0.69 | POLB (0.46) | CYP2C19HIF1ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10912464 | 0.68 | TAAR1 (0.48) | ALDH1A1CYP2C19HIF1ACYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008005542-A2 | ANTIVIRAL PHOSPHINATE COMPOUNDS | GILEAD SCIENCES, INC., (US) | 2008-01-10 | — | — | WO | disclosed |