SCHEMBL1024978

SCHEMBL1024978

C[C](CCC(C)(C)c1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.45
CYP2C19 P33261 1/20 0.37
HIF1A Q16665 1/20 0.37
ALDH1A1 P00352 3/20 0.36
ALOX15 P16050 1/20 0.36
HTT P42858 1/20 0.36
ESR1 P03372 2/20 0.35
ESR2 Q92731 2/20 0.35
CYP3A4 P08684 1/20 0.35
MAPK1 P28482 1/20 0.34
SHBG P04278 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
CES1 P23141 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
CES2 O00748 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1019327 0.80 TAAR1 (0.48) TAAR1CYP2C19HIF1AALDH1A1ALOX15
SCHEMBL25340770 0.79 L3MBTL1 (0.52) TAAR1CYP2C19HIF1AALDH1A1ALOX15
SCHEMBL30464748 0.78 TAAR1 (0.47) TAAR1CYP2C19HIF1AALDH1A1ALOX15
SCHEMBL16369386 0.78 ALDH1A1 (0.48) TAAR1CYP2C19HIF1AALDH1A1ALOX15
SCHEMBL3368788 0.76 TAAR1 (0.64) TAAR1CYP2C19HIF1AALDH1A1ALOX15
SCHEMBL3298136 0.76 CES1 (0.46) ALDH1A1ALOX15HTTESR1CYP3A4
SCHEMBL1682512 0.76 HIF1A (0.53) TAAR1CYP2C19HIF1AALDH1A1HTT
SCHEMBL10828942 0.74 TAAR1 (0.42) TAAR1CYP2C19HIF1AALDH1A1ALOX15
SCHEMBL10380677 0.73 CYP2C19 (0.50) TAAR1CYP2C19HIF1AALDH1A1ALOX15
SCHEMBL873051 0.73 TAAR1 (0.54) TAAR1CYP2C19HIF1AALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2998017-B1 ADDITION COMPOUNDS SUITABLE AS DISPERSANTS OR ANTI-SEDIMENTATION AGENTS EVONIK DEGUSSA GMBH (DE) 2019-11-13 EP disclosed
US-9574044-B2 Addition compounds suitable as dispersants or anti-sedimentation agents EVONIK DEGUSSA GMBH (DE) 2017-02-21 US disclosed
US-20160083502-A1 ADDITION COMPOUNDS SUITABLE AS DISPERSANTS OR ANTI-SEDIMENTATION AGENTS EVONIK DEGUSSA GMBH (DE) 2016-03-24 US disclosed
EP-2998017-A1 ADDITION COMPOUNDS SUITABLE AS DISPERSANTS OR ANTI-SEDIMENTATION AGENTS Evonik Degussa GmbH (DE) 2016-03-23 EP disclosed
US-8772371-B2 Pearlescent pigments coated with a metal oxide/hydroxide layer and an acrylic copolymer BASF SE (DE) 2014-07-08 US disclosed
US-20110118384-A1 PEARLESCENT PIGMENTS COATED WITH A METAL OXIDE/HYDROXIDE LAYER AND AN ACRYLIC COPOLYMER BASF SE (DE) 2011-05-19 US disclosed
EP-2274382-A1 PEARLESCENT PIGMENTS COATED WITH A METAL OXIDE/HYDROXIDE LAYER AND AN ACRYLIC COPOLYMER BASF SE (DE) 2011-01-19 EP disclosed
WO-2009135784-A1 PEARLESCENT PIGMENTS COATED WITH A METAL OXIDE/HYDROXIDE LAYER AND AN ACRYLIC COPOLYMER BASF SE (DE) 2009-11-12 WO disclosed
US-7410504-B2 Adducts based on cyclic compounds and the use thereof as tanning agents and curing agents BASF AKTIENGESELLSCHAFT (DE) 2008-08-12 US disclosed
US-7268203-B2 Polymer dispersant having hyperbranched structures BASF AKTIENGESELLSCHAFT (DE) 2007-09-11 US disclosed
US-20070022541-A1 Method for producing leather BASF AKTIENGESSELLSCHAFT (DE) 2007-02-01 US disclosed
US-20060101583-A1 Adducts based on cyclic compounds and the use thereof as tanning agents and curing agents BASF AKTIENGESELLSCHAFT (DE) 2006-05-18 US disclosed
US-7022786-B2 Ligands, complexes and their use for the polymerization of olefins BASF AKTIENGESELLSCHAFT (DE) 2006-04-04 US disclosed
US-20050038212-A1 Ligands, complexes, and their use for the polymerization of olefins BASF AKTIENGESELLSCHAFT (DE) 2005-02-17 US disclosed
EP-1488013-A1 USE OF POLYELECTROLYTES IN THE PRODUCTION OF LEATHER BASF AKTIENGESELLSCHAFT (DE) 2004-12-22 EP disclosed
US-20040097685-A1 Novel polymer dispersant having hyperbranched structures BASF SE (DE) 2004-05-20 US disclosed
EP-1368389-A1 COMPLEXED COMPOUNDS AND USE THEREOF FOR THE POLYMERISATION OF OLEFINS BASF AKTIENGESELLSCHAFT (DE) 2003-12-10 EP disclosed
WO-2003078664-A1 USE OF POLYELECTROLYTES IN THE PRODUCTION OF LEATHER BASF AKTIENGESELLSCHAFT (DE) 2003-09-25 WO disclosed
US-6559326-B1 Substituted phosphinophenoxide-metal complexes for the polymerization of olefins BASF AKTIENGESELLSCHAFT (DE) 2003-05-06 US disclosed
WO-2002064644-A1 COMPLEXED COMPOUNDS AND USE THEREOF FOR THE POLYMERISATION OF OLEFINS BASF AKTIENGESELLSCHAFT (DE) 2002-08-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038212-A1 Ligands, complexes, and their use for the polymerization of olefins RPS10, RNF10, NOP10 TAAR1 543/4885CYP2C19 4368/4885HIF1A 1427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.