Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777456 | 0.99 | POLB (0.41) | ALDH1A1POLBATML3MBTL1CHRM3 | |
| SCHEMBL4780966 | 0.82 | HTR2C (0.45) | ALDH1A1POLBCHRM3CYP2D6LMNA | |
| SCHEMBL4778023 | 0.82 | CHRM3 (0.39) | ALDH1A1ATML3MBTL1CHRM3CYP2D6 | |
| SCHEMBL4727371 | 0.77 | CHRM3 (0.43) | ALDH1A1POLBATML3MBTL1CHRM3 | |
| SCHEMBL14291316 | 0.77 | ALDH1A1 (0.41) | ALDH1A1POLBATML3MBTL1CHRM3 | |
| SCHEMBL14291869 | 0.76 | POLB (0.40) | ALDH1A1POLBATML3MBTL1CHRM3 | |
| SCHEMBL13329443 | 0.76 | ALDH1A1 (0.40) | ALDH1A1POLBATML3MBTL1CHRM3 | |
| SCHEMBL3215013 | 0.76 | CHRM3 (0.42) | ALDH1A1POLBATML3MBTL1CHRM3 | |
| SCHEMBL4793046 | 0.76 | CHRM3 (0.43) | ALDH1A1POLBATML3MBTL1CHRM3 | |
| SCHEMBL3218882 | 0.76 | ALDH1A1 (0.40) | ALDH1A1POLBATML3MBTL1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008023157-A1 | NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS USEFUL AS M3-RECEPTOR MODULATORS | ARGENTA DISCOVERY LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |
| WO-2008023157-A1 | NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS USEFUL AS M3-RECEPTOR MODULATORS | ARGENTA DISCOVERY LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |