Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 13/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.50 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725039 | 0.92 | CYSLTR1 (0.57) | PDE10ACYP1A2CYSLTR2CYSLTR1 | |
| SCHEMBL4783734 | 0.91 | PDE10A (0.59) | PDE10ACYP1A2LGALS3PDE4DCYSLTR2 | |
| SCHEMBL4730048 | 0.89 | PDE10A (0.44) | PDE10ACYP1A2LGALS3PDE4DCYSLTR2 | |
| SCHEMBL4728459 | 0.88 | PDE10A (0.56) | PDE10ACYP1A2CYSLTR2CYSLTR1 | |
| SCHEMBL4725624 | 0.83 | PDE10A (0.60) | PDE10ACYP1A2CYSLTR2CYSLTR1 | |
| SCHEMBL4726967 | 0.82 | PDE10A (0.52) | PDE10ACYP1A2LGALS3PDE4D | |
| SCHEMBL4726394 | 0.82 | PDE10A (0.52) | PDE10ACYP1A2LGALS3PDE4D | |
| SCHEMBL4725570 | 0.81 | IP6K1 (0.50) | — | |
| SCHEMBL4727365 | 0.81 | PIK3CD (0.51) | PDE10ACYP1A2CYSLTR2CYSLTR1 | |
| SCHEMBL4780024 | 0.80 | CYSLTR1 (0.51) | PDE10ACYP1A2CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020302-A2 | HETEROAROMATIC QUINOLINE-BASED COMPOUNDS AS PHOSPHODIESTERASE (PDE) INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-02-21 | — | — | WO | claimed |