SCHEMBL4725567

SCHEMBL4725567

CC/C(=N/OCc1nc2ccccc2c(=O)n1C)c1ccc(OC(CC)C(=O)O)cc1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.47
ALOX15 P16050 1/20 0.47
TSHR P16473 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
HDAC6 Q9UBN7 2/20 0.43
PPARG P37231 4/20 0.43
PPARA Q07869 3/20 0.43
ACKR3 P25106 6/20 0.42
HDAC8 Q9BY41 1/20 0.41
RXFP1 Q9HBX9 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
UBE2I P63279 1/20 0.39
SAE1 Q9UBE0 1/20 0.39
UBA2 Q9UBT2 1/20 0.39
AURKB Q96GD4 1/20 0.39
PDE10A Q9Y233 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4728606 0.81 SAE1 (0.44) KDM4EALOX15TSHRTDP1L3MBTL1
SCHEMBL4845938 0.81 SAE1 (0.44) KDM4EALOX15TSHRTDP1L3MBTL1
SCHEMBL4725571 0.80 KDM4E (0.45) KDM4EALOX15TSHRTDP1L3MBTL1
SCHEMBL15543639 0.78 ALDH1A1 (0.49) KDM4EALOX15TSHRTDP1L3MBTL1
SCHEMBL15543189 0.78 ALDH1A1 (0.49) KDM4EALOX15TSHRTDP1L3MBTL1
SCHEMBL6555833 0.74 KDM4E (0.62) KDM4EALOX15TSHRTDP1L3MBTL1
SCHEMBL4729782 0.73 PPARG (0.49) PPARGPPARASMN1; SMN2
SCHEMBL4729785 0.73 PPARG (0.49) PPARGPPARASMN1; SMN2
SCHEMBL4730159 0.73 PPARG (0.56) PPARGPPARA
SCHEMBL4728538 0.73 PPARG (0.56) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO claimed
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO disclosed