Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 2/20 | 0.43 |
| ▸ | BRAF | P15056 | 16/20 | 0.41 |
| ▸ | RAF1 | P04049 | 14/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725055 | 0.90 | TEK (0.43) | TEKBRAFRAF1 | |
| SCHEMBL4726696 | 0.85 | RAF1 (0.41) | BRAFRAF1 | |
| SCHEMBL4727584 | 0.84 | RAF1 (0.41) | BRAFRAF1 | |
| SCHEMBL4729575 | 0.84 | MAPK14 (0.40) | BRAFRAF1CYP2C9 | |
| SCHEMBL4727954 | 0.83 | RAF1 (0.49) | BRAFRAF1 | |
| SCHEMBL4725952 | 0.83 | RAF1 (0.41) | TEKBRAFRAF1 | |
| SCHEMBL4725070 | 0.83 | TEK (0.46) | TEKBRAFRAF1 | |
| SCHEMBL4727416 | 0.82 | RAF1 (0.43) | TEKBRAFRAF1 | |
| SCHEMBL4782747 | 0.81 | RAF1 (0.46) | TEKBRAFRAF1 | |
| SCHEMBL4726247 | 0.81 | RAF1 (0.43) | TEKBRAFRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |