Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.40 |
| ▸ | BRAF | P15056 | 13/20 | 0.39 |
| ▸ | RAF1 | P04049 | 9/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782257 | 0.86 | MAPK14 (0.44) | MAPK14BRAFRAF1TRPV1 | |
| SCHEMBL4729579 | 0.84 | MAPK14 (0.40) | MAPK14BRAFRAF1TRPV1 | |
| SCHEMBL4728370 | 0.84 | MAPK14 (0.45) | MAPK14BRAFRAF1TRPV1 | |
| SCHEMBL4727823 | 0.84 | MAPK14 (0.45) | MAPK14BRAFRAF1TRPV1 | |
| SCHEMBL4725947 | 0.84 | TEK (0.43) | BRAFRAF1CYP2C9 | |
| SCHEMBL4729989 | 0.82 | MAPK14 (0.43) | MAPK14BRAFRAF1TRPV1 | |
| SCHEMBL4725596 | 0.82 | MAPK14 (0.40) | MAPK14BRAFRAF1TRPV1 | |
| SCHEMBL4729144 | 0.81 | MAPK14 (0.41) | MAPK14BRAFRAF1TRPV1 | |
| SCHEMBL4725981 | 0.81 | MAPK14 (0.42) | MAPK14BRAFRAF1TRPV1 | |
| SCHEMBL4730324 | 0.81 | MAPK14 (0.42) | MAPK14BRAFRAF1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |