Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 11/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 10/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | MARK3 | P27448 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | PRKX | P51817 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778605 | 0.91 | ROCK1 (0.42) | ROCK1ROCK2TRPV1MAPK1AURKA | |
| SCHEMBL4726089 | 0.91 | TSHR (0.50) | ROCK1ROCK2TRPV1MAPK1AURKA | |
| SCHEMBL4726401 | 0.90 | LMNA (0.42) | ROCK1ROCK2TRPV1MAPK1AURKA | |
| SCHEMBL4725694 | 0.89 | ROCK1 (0.44) | ROCK1ROCK2TRPV1MAPK1AURKA | |
| SCHEMBL4778546 | 0.88 | ROCK1 (0.44) | ROCK1ROCK2TRPV1MAPK1AURKA | |
| SCHEMBL4780515 | 0.87 | TSHR (0.41) | ROCK1ROCK2TRPV1MAPK1AURKA | |
| Hydrochloric Acid SCHEMBL4779977 | 0.87 | ROCK1 (0.43) | ROCK1ROCK2TRPV1MAPK1AURKA | |
| SCHEMBL4780046 | 0.87 | TSHR (0.46) | ROCK1ROCK2TRPV1MAPK1AURKA | |
| SCHEMBL4777271 | 0.87 | ROCK1 (0.48) | ROCK1ROCK2TRPV1MAPK1AURKA | |
| SCHEMBL4777329 | 0.87 | ROCK1 (0.43) | ROCK1ROCK2TRPV1MAPK1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008011191-A1 | ANTIBACTERIAL HETEROCYCLIC UREAS | REPLIDYNE, INC. (US) | 2008-01-24 | — | — | WO | claimed |
| WO-2008011191-A1 | ANTIBACTERIAL HETEROCYCLIC UREAS | REPLIDYNE, INC. (US) | 2008-01-24 | — | — | WO | disclosed |