Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 15/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 10/20 | 0.47 |
| ▸ | CHRNA2 | Q15822 | 10/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8508105 | 0.90 | CHRNB2 (0.47) | CHRNB2CHRNA3CHRNA2CHRNA4CHRNB4 | |
| SCHEMBL6231725 | 0.90 | CHRNB2 (0.59) | CHRNB2CHRNA3CHRNA2CHRNA4CHRNB4 | |
| SCHEMBL8508784 | 0.90 | CHRNB2 (0.47) | CHRNB2CHRNA3CHRNA2CHRNA4CHRNB4 | |
| SCHEMBL4725595 | 0.90 | CHRNB2 (0.52) | CHRNB2CHRNA3CHRNA2CHRNA4CHRNB4 | |
| SCHEMBL6235459 | 0.90 | CHRNB2 (0.51) | CHRNB2CHRNA3CHRNA2CHRNA4CHRNB4 | |
| SCHEMBL4779799 | 0.90 | CHRNB2 (0.51) | CHRNB2CHRNA3CHRNA2CHRNA4CHRNB4 | |
| SCHEMBL4779724 | 0.89 | CHRNB2 (0.58) | CHRNB2CHRNA3CHRNA2CHRNA4CHRNB4 | |
| Hydrochloric Acid SCHEMBL8584830 | 0.89 | CHRNB2 (0.58) | CHRNB2CHRNA3CHRNA2CHRNA4CHRNB4 | |
| SCHEMBL8508192 | 0.89 | CHRNB2 (0.45) | CHRNB2CHRNA3CHRNA2CHRNA4CHRNB4 | |
| SCHEMBL8506710 | 0.85 | CHRNB2 (0.42) | CHRNB2CHRNA3CHRNA2CHRNA4CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008011484-A2 | NICOTINIC DESENSITIZERS AND METHODS OF SELECTING, TESTING, AND USING THEM | BETHESDA PHARMACOLOGY ASSOCIATES, LLC (US) | 2008-01-24 | — | — | WO | disclosed |