Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 10/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5440780 | 0.84 | SOS1 (0.71) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL5440784 | 0.84 | SOS1 (0.71) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL11049170 | 0.80 | MAPT (0.69) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL14935499 | 0.80 | MAPT (0.69) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL9978289 | 0.80 | MAPT (0.69) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL7192692 | 0.80 | MAPT (0.56) | RAB9ANPC1MEN1KMT2AGAA | |
| SCHEMBL29414981 | 0.79 | SOS1 (0.65) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL566396 | 0.79 | SOS1 (0.65) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL446484 | 0.79 | SOS1 (0.65) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL3846862 | 0.79 | SOS1 (0.65) | RAB9ANPC1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021250-A2 | COMPOSITIONS AND METHODS FOR MODULATING APOPTOSIS IN CELLS OVER-EXPRESSING BCL-2 FAMILY MEMBER PROTEINS | FRED HUTCHINSON CANCER RESEARCH CENTER (US) | 2008-02-21 | — | — | WO | disclosed |